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EC number: 436-710-6 | CAS number: 756-13-8
Remark lipid content:
Lipid content (LO) represents the average lipid content at termination of testing. Lipid content (HI) represents the average lipid content prior to testing. Each value represents an average of three determinations, each using combined tissue from two fish.
Lipid content was measured using three sets of two each control fish taken prior to the testing and at the termination of the testing period. The fish were measured and weighed, minced, and homogenized as is. A weighed portion of the homogenate was extracted with chloroform – methanol (ratio not specified), and the residue after solvent removal measured gravimetrically. Results represent the average of three determinations at each of the two time points.
In a 28-day bioconcentration study, carp (Cyprinus carpio) were exposed to PFPA at nominal and measured concentrations of 1 and 0.1 mg/L, 0.918 (+0.0315) and 0.0923 (+0.00907) mg/L respectively under continuous flow through conditions. The 28 day BCF was 1.2 and<4.8 for the 1 and 0.1 mg/L exposures respectively. No sublethal effects were observed in the test groups. Based on the results of this study, PFPA would not be classified as bioaccumulative in Carp.
While a few data points are missing (e.g. report of actual fish weight, descr. of behavioral patterns observed for determination of “abnormalitites in behavior”) the quality of the data reported and conclusions are not diminished. This bioconcentration study is classified as acceptable and satisfies the guideline requirement for Bioconcentration study in Carp.
Test organism size/age: Yearling carp, 7.7 - 9.6 cm; estimated to be ~10 g/fish
Test Type: Flowthrough
BCF Level 1 (1 mg/L): 1.2
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