Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 1998-02-13 to 1998-06-17
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1998
Report Date:
1998

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to
Guideline:
other: Directive 92/69/CEE, Méthode A 6 Méthode Elution sur Colonne.
GLP compliance:
yes (incl. certificate)
Remarks:
1998-05-28
Type of method:
column elution method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Identification of the flask: Lipacide UG / Lot: 98 043 300
- Appearence: white powder
- Packaging: plastic bag
- Received: 1998-04-02
- Storage: in darkness at room temperature
- Identification number for the study: 98021

Results and discussion

Water solubility
Water solubility:
ca. 81 mg/L
Temp.:
20 °C
pH:
<= 5

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
the solubility in water at 20.2 °C of the test substance was:
81 mg/L
Executive summary:

Test objective:

to determine the water solubility of the test substance at a given temperature

POCEDURE

The solubility in water of a subsatnce is specified by the saturation mass concentration of the test substance in water at a given temperature.

A preliminary trial was performed to determine the approximate amount of the sample and the time necessary to achieve the saturation mass concentration.

The results of the test allowed to select the appropriate method: if solubility is less than 10^-2 g/L, the column elution is used, if not, the flask method is used.

METHOD:

The column elution method was used.

5 samples were analyzed.

The repetability was inferior to 30%: 18.9% maximum

RESULTS:

The solubility in water at 20.2 °C of the test substance was:

81 mg/L