Registration Dossier
Registration Dossier
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EC number: 466-490-7 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Study reports have been available for acute tests with fish, invertebrate, algae and micro-organism. The results are summarized as below:
The acute toxicity of the test item to zebra fish was determined in a 96-hour static test according to OECD TG 203. 100 mg/L of test substance and a control were applied in the limit test. The LC50, LOEC and LC100 could not be quantified due to the absence of a toxic effect of the test item at the tested concentration, but showed that LC50, LC100 and NOEC of the test substance were all above 100 mg/L.
The acute toxicity of the test item to Daphnia magna was determined in a 48-hour static test according to OECD TG 202. 100 mg/L of test substance and a control were applied in the limit test. The 48-hour NOEC and the 48-hour EC0 of test substance to daphnia magna were determined to be at least 100 mg/L. The 48-hour EC50 and the 48-hour EC100 were clearly higher than 100 mg/L.
The influence of the test item on the growth of the green algal species Scenedesmus subspicatus was investigated in a 72-hour static test according to the modified OECD TG 201 under GLP principle compliance condition. 4.6, 10, 22, 46 and 100 mg/L and a control of the test substance were applied in the definitive test. The results where the algae grew in the test media with dissolved test item as in a usual algal growth inhibition test were taken into consideration for the determination of the toxic effect of the test item on the growth Scenedesmus subspicatus. The result of Experiment A indicated ErC50 was above 100 mg/L, NOEC was 10 mg/L and LOEC was 22 mg/L.
The inhibitory effect of the test item on the respiration rate of aerobic wastewater microorganisms of activated sludge was investigated in 3-hour respiration inhibition test according to the OECD TG 209. Only one concentration of 1000 mg/L of test substance was applied in the definitive test. Control groups and reference substance were also applied. The results indicated 3-hour NOEC of the test item to activated sludge microorganisms was at least 1000 mg/L. This value might even be higher but concentrations above 1000 mg/L were not tested. The 3-hour EC20, EC50, and EC80 could not be calculated, but were clearly higher than 1000 mg/L.
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