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Partition coefficient

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Description of key information

The partition coefficient, log POW, of FAT 40825/A was calculated from the individual solubilities in n-octanol and in water, respectively, to be:<= -4.7.

Key value for chemical safety assessment

Log Kow (Log Pow):
-4.7
at the temperature of:
20 °C

Additional information

Neither the HPLC-method according to OECD Guideline No. 117 nor the flask-shaking method according to OECD Guideline No. 107 were applicable for the determination of the partition coefficient of FAT 40825/A. Thus, the log POW-value for the test item was estimated from its solubility in n-octanol and in water, respectively.

In the present study, the n-octanol solubility of FAT 40825/A was determined to be about 6.6 µg/ml. The water solubility of FAT 40825/A was found to be at least 341 g/l at room temperature.

In conclusion, the partition coefficient, log POW, of FAT 40825/A was calculated from the individual solubilities in n-octanol and in water, respectively, to be <= -4.7.