Registration Dossier
Registration Dossier
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EC number: 437-970-3 | CAS number: 371921-62-9
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Red 0106-PP1
- IUPAC Name:
- Red 0106-PP1
Constituent 1
Results and discussion
- Transformation products:
- not measured
Total recovery of test substance (in %)
- Remarks on result:
- not determinable because of methodological limitations
- Remarks:
- The test substance is insoluble in water
Dissipation DT50 of parent compound
- Remarks on result:
- not determinable because of methodological limitations
- Remarks:
- The test substance is insoluble in water
Any other information on results incl. tables
The solubility of the test substance in the buffer solutions pH 4.0, pH 7.0 and pH 9.0 was very low. lt was not possible to increase the solubility of the test item with the use of different solubilizers (acetonitrile, acetone, dimethylsulfoxide and dimethylformamide). Peaks obtained, if any, were too small to allow quantification or even to follow a degradation curve.
.
According to the EEC Directive 92169, Section C.7, the method is applicable only to water soluble substances. The test item shows no significant solubility in the different solvent systems. Therefore, no further testing could be performed with the test substance at the
different pH values.
Applicant's summary and conclusion
- Conclusions:
- No conclusion on hydrolisis of the test substance can be made as it shows no significant solubility neither in water nor in the different solvent systems
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