Trisiloxane, 3-ethyl-1,1,1,3,5,5,5-heptamethyl-

Hydrolysis

Administrative data

Endpoint:

hydrolysis

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is highly insoluble in water

Justification for type of information:

The hydrolytical stability of the test item could not be determined using a procedure designed to be compatible with Method C.7 Abiotic Degradation, Hydrolysis as a Function of pH of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 111 of the OECD Guidelines for Testing of Chemicals, 13 April 2004, due to the low solubility of the test item in aqueous media.
The water solubility was found to be very low (<= 0.1 mg/L (22°C; pH=5.5)).

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2005-06-20 to 2006-01-018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

1992

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

July 1995

Deviations:

no

GLP compliance:

yes

Type of method:

flask method

Specific details on test material used for the study:

Storage: room temperature

Water solubility:

<= 0.1 mg/L

Temp.:

22 °C

pH:

5.5

Details on results:

According to the results of the pre-test the water solubility of the test item was below 1 mg/L.
The linearity of the analytical method was proven in the concentration range from 0.2 to 1 mg test item/L.

Conclusions:

The water solubility of the test item was estimated to be <= 0.1 mg/L (mean value, 0.033 mg/L standard deviation) at 22°C ± 1°C.