Registration Dossier
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EC number: 202-805-4 | CAS number: 99-97-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
Biodegradation :
Biodegradation in water: screening tests :
Weight of evidence studies reviewed for biodegradation in water from reliable sources having Klimish rating 2.
The summary of the results is presented below:
Sr.No | Endpoint | Half-life | Remark | Sources |
1 | Biodegradation in water | - | Not readily biodegradable | Predicted data of Target chemical |
2 | Biodegradation in water | - | Not Readily biodegradable | Data is from database from CAS NO 91-66-7 |
Based on the study and predicted data, it is concluded that the chemical is persistent in water medium
Biodegradation in water and sediment :
As per biowin model N,N-dimethyl-p-toluidine is not readily biodegradable in water as the Biowin3 (ultimate survey model) result is p = 2.5707 months ( if in days or weeks then readily biodegradable), AND the Biowin5 (MITI linear model) probability is p= 0.3002 ( less than 0.5 is not readily biodegradable), while on the basis of fugacity model half life of N,N-dimethyl-p-toluidine in sediment is 337.5 days (8100 hrs.).Based on these half life values of it is concluded that N,N-dimethyl-p-toluidine is non biodegradable in sediment. However, since there is negligible diffusion of the substance in the sediment medium as evident from the reported data (0.175%) and hence persistence in the sediment compartment is not likely to be critical.
Biodegradation in soil :
Based on level III fugacity model halflife period ofN,N-dimethyl-p-toluidine was estimated.
Half life period of N,N-dimethyl-p-toluidine in Soil was observed to be 75 days which does not exceeds the threshold criteria of 120 days. Based on these half life values it is concluded that N,N-dimethyl-p-toluidine is readily biodegradable (not persistent) in Soil medium
Media | Half life (Days) | % in medium |
Soil | 75 | 78 |
Media | Half life (hrs) | % in medium | Emissions (kg/hr) |
Soil | 1800 | 78 | 1000 |
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