Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2006
Report Date:
2006

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Test conditions

Hardness:
277 mg CaCO3/L
Test temperature:
20.4 - 20.5°C
pH:
8.1
Dissolved oxygen:
8.2 - 8.3 mg/L
Reference substance (positive control):
no

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
11.67 mg/L
Nominal / measured:
nominal
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
4.04 mg/L
Nominal / measured:
nominal
Duration:
48 h
Dose descriptor:
EC100
Effect conc.:
16 mg/L
Nominal / measured:
nominal
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
1 mg/L
Nominal / measured:
nominal

Any other information on results incl. tables

The results are expressed in terms of nominal concentrations. Recovery rates ranged from 119.2 - 172.7 % of nominal values at 0 hours, and from 119.7 - 172.7 % of nominal values at 48 hours, respectively. The high recovery of 172.7 % in the lowest concentration was determined close to the limit of quantification. It has no impact on the study result.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
NOEC (48 h): 1 mg/L