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Administrative data

Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Testing was conducted between 14 November 2002 and 06 December 2002. Final report was issued 31 January 2003.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Meets the criteria for classification as Reliable without restriction according to Klimisch et al (1997)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2003
Report Date:
2003

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Method C19 of Commission Directive 2001/59/EC - HPLC Screening Method
Deviations:
no
GLP compliance:
yes
Type of method:
other: HPLC screening method
Media:
other: HPLC Column

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid
Radiolabelling:
no

Study design

Test temperature:
40°C (column temperature)

HPLC method

Details on study design: HPLC method:
EQUIPMENTHPLC system : Agilent Technologies 1100, incorporating autosampler and workstationColumn : Phenosphere Next 5u CN (250 x 4.6 mm id)Column temperature : 40 degrees CFlow rate : 1 ml/minInjection volume : 10ulUV detector wavelength: dead time and reference standards: 210 nm, sample: 254 nmMOBILE PHASES- Type: methanol:reverse osmosis water (55:45 v/v) adjusted to approx. neutral pH with 0.1M NaOH- pH: 7.1DETERMINATION OF DEAD TIME- Method: dead time determined by measuring the retention time of formamideREFERENCE SUBSTANCES- Identity: Acetanilide, Atrazine, Isoproturon, Triadimenol, Linuron, Naphthalene, Endosulfan-diol, Fenthion, Phenanthrene, DDT

Batch equilibrium or other method

Analytical monitoring:
no

Results and discussion

Adsorption coefficient
Key result
Sample No.:
#1
Type:
log Koc
Value:
< 1.25 dimensionless
pH:
7.1

Results: HPLC method

Details on results (HPLC method):
- Retention times of reference substances used for calibration: Acetanilide 3.654 Atrazine 3.985 Isoproturon 4.182 Triadimenol 4.426 Linuron 4.578Naphthalene 4.709Endosulfan-diol 4.802Fenthion 5.480 Phenanthrene 5.813 DDT 9.522- Details of fitted regression line (log k' vs. log Koc): r= 0.980- Average retention data for test substance: 1.487

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The adsorption coefficient (Koc) of the test material has been determined to be <17.8, log10 Koc <1.25.
Executive summary:

Introduction

The study was carried out to assess the adsorption coefficient (KOC) of the test substance using the using the HPLC screening method, Method C19 of Commission Directive 2001159/EC (which constitutes Annex V of Council Directive 67 /548/EEC).

Results and conclusion

The adsorption coefficient (Koc) of the test material has been determined to be less than 17.8 and log10Koc<1.25.