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Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Testing was conducted between 04 March 2005 and 30 March 2005. The final report was issued 13 June 2005.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Meets the criteria for classification as Reliable without restriction according to Klimisch et al (1997).

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report Date:
2005

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
< -3.06
Temp.:
22 °C
pH:
7

Any other information on results incl. tables

Substances having a log10 Pow of greater than 3 are regarded as having the potential to bioaccumulate in the environment.

The n-octanol saturated water was adjusted to pH 7 to ensure the test material was partitioned at an environmentally relevant pH.

The limit value used for calculating the organic phase concentrations was taken from the lowest absorbance seen in the analysis of the organic standards.

Applicant's summary and conclusion

Conclusions:
The partition coefficient was determined to be less than 8.86 x 104 at 22.0 ± 0.5°C, log10 Pow less than -3.06.
Executive summary:

Introduction.

The partition coefficient of the test substance was determined using the shake flask method , according to the Method A8 of commission directive 92/69/EEC (which constitutes Annex V of council directive 67/548/EEC.

Results and discussion

Using the shake flask method the partition coefficient was determined to be less than 8.86 x 104 at 22.0 ± 0.5°C, log10 Pow is less than -3.06.