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EC number: 410-440-9 | CAS number: 164058-20-2
In an eye irritation study according to OECD Guideline 405 a single introduction of 100 mg (E)-5[(4 - chlorophenyl)methylene]-2,2 - dimethylcyclopentanone
One hour and 24 hours after introduction of the test substunce, slight conjunctival reactions (chemosis und redness) were observed. After 24 hours in 2 animals and after 48 hours in one animal, a slight corneal opacity was noted. A myosis appeared in 2 animals after 24 hours und then disappeared at the 48 -hour scoring period. After 72 hours, all ocular reactions were reversible in the 3 animals.
Thus, the test substance was considered as non-irritant when administered by ocular route in rabbits.
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