Registration Dossier
Registration Dossier
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EC number: 225-511-8 | CAS number: 4890-85-1
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- publication
- Title:
- Developmental Toxicity
- Author:
- Developmental Toxicity model (CAESAR) (version 2.1.6)
- Bibliographic source:
- VEGA NIC (version 2.1.8)
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: General model for estimating the development toxicity
- Principles of method if other than guideline:
- no data
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- o-phenethylbenzoic acid
- EC Number:
- 225-511-8
- EC Name:
- o-phenethylbenzoic acid
- Cas Number:
- 4890-85-1
- Molecular formula:
- C15H14O2
- IUPAC Name:
- 2-(2-phenylethyl)benzoic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Results and discussion
Results: maternal animals
Maternal developmental toxicity
- Details on maternal toxic effects:
- Maternal toxic effects:no data
Effect levels (maternal animals)
- Dose descriptor:
- other: qualitative result by model
- Based on:
- test mat.
- Basis for effect level:
- other: developmental toxicity
Results (fetuses)
- Details on embryotoxic / teratogenic effects:
- Embryotoxic / teratogenic effects:no data
Fetal abnormalities
- Abnormalities:
- not specified
Overall developmental toxicity
- Developmental effects observed:
- not specified
Any other information on results incl. tables
Model assessment: Prediction is Toxicant and the result appears reliable.
Details are provided in attachment on the section: "attached full study report".
Applicant's summary and conclusion
- Conclusions:
- The prediction of the model is toxicant and the result appears reliable.
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