Registration Dossier

Administrative data

Endpoint:
stability: thermal, sunlight, metals, other
Remarks:
Migrated from section 'Stability: thermal, sunlight, metals'
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: well performed study according to internal standards

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: company SOP
Principles of method if other than guideline:
Determination of the decomposition temperature via DSC.
Apparatus: Mettler Toledo, DSC 821e
Conditions: 25 – 450°C, 3 K/min, sealed glass vial in air
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzamide, 3-amino-N-[4-(aminocarbonyl)phenyl]-4-methoxy-, hydrochloride
EC Number:
618-990-3
Cas Number:
939961-06-5
Molecular formula:
C15H15N3O3xClH
IUPAC Name:
Benzamide, 3-amino-N-[4-(aminocarbonyl)phenyl]-4-methoxy-, hydrochloride
Details on test material:
Purity: 94.7 % (w/w)

Results and discussion

For thermal stability study

Test substance thermally stable:
no
Operating temperature
Operating temp.:
> 25 - < 450 °C
Remarks on result:
other: decomposition starts at 277 °C.
Sublimation:
no
Transformation products:
not measured

For study on stability to sunlight

Test substance stable to sunlight:
not determined

For study on stability to metals

Test substance stable to metals / metal ions:
not determined

Applicant's summary and conclusion

Conclusions:
The substance decomposes at 277°C.
Executive summary:

The decomposition temperature was determined by DSC with a Mettler, DSC 821e apparatus. The temperature range was from 25 to 450 ° an the heating rate was 3 K/min. The substance was capsuled in a sealed glass vial in air. The decomposition temperature was found to be

277 °C.