Registration Dossier

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Reliable source; detailed documentation not available

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1999

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method B.13/14 (Mutagenicity - Reverse Mutation Test Using Bacteria)
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
4-amino-2,4-dihydro-5-(1-methylethyl)-3H-1,2,4-triazol-3-one
EC Number:
689-404-1
Cas Number:
96240-10-7
Molecular formula:
C5H10N4O
IUPAC Name:
4-amino-2,4-dihydro-5-(1-methylethyl)-3H-1,2,4-triazol-3-one

Results and discussion

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
negative with metabolic activation
negative without metabolic activation