Registration Dossier

Administrative data

Endpoint:
skin sensitisation: in vivo (non-LLNA)
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Reliable source; detailed documentation not available

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1999

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method B.6 (Skin Sensitisation)
GLP compliance:
not specified
Type of study:
guinea pig maximisation test

Test material

Constituent 1
Chemical structure
Reference substance name:
4-amino-2,4-dihydro-5-(1-methylethyl)-3H-1,2,4-triazol-3-one
EC Number:
689-404-1
Cas Number:
96240-10-7
Molecular formula:
C5H10N4O
IUPAC Name:
4-amino-2,4-dihydro-5-(1-methylethyl)-3H-1,2,4-triazol-3-one

In vivo test system

Test animals

Species:
guinea pig
Strain:
not specified
Sex:
female

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Under test conditions the TS exhibits no skin-sensitization potential.