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Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP status not known, information from published handbook, acceptable with restrictions

Data source

Reference
Reference Type:
review article or handbook
Title:
CRC Handbook of Chemistry and Physics, 89th Edition.
Author:
Lide, D. (Ed)
Year:
2008
Bibliographic source:
CRC Press Inc. Boca Raton. USA.

Materials and methods

Principles of method if other than guideline:
The use of secondary sources of data is acceptable when they are based on a critical evaluation of peer-reviewed data and a consequent selection of a reliable and representative value for the property under investigation. The introduction to the CRC Handbook of Chemistry and Physics states that data for physical constants have been taken from many sources, including both compilations and the primary literature. Where conflicts were found, the value deemed most reliable was chosen. Therefore, although the method used is not known, the values presented here are acceptable as they are from a reliable secondary source of phys chem. data.
GLP compliance:
not specified
Type of method:
other: No data reported
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
No data reported

Study design

Analytical method:
not specified

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-0.17
Temp.:
25 °C
pH:
7
Details on results:
No data reported. pH and temperature assumed.

Applicant's summary and conclusion

Conclusions:
The log Pow of acetic acid is -0.17
Executive summary:

No information on the primary source of this data or the methods used is available. However, this information is taken from a reliable peer reviewed handbook and so can be considered reliable and suitable for use as the key study for this endpoint.