Registration Dossier

Administrative data

Description of key information

The acute oral median lethal dose (LD50) of PC2414 was estimated to be greater than 2000 mg/kg bw. In accordance with the Globally Harmonised Classification System PC2414 is not classified. 

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

The acute oral toxicity of PC2414 was assessed in rats using the fixed dose method as described in OECD guideline 420 and EC guideline B1. The acute oral median lethal dose (LD50) of PC2414 was estimated to be greater than 2000 mg/kg bw.

Justification for classification or non-classification

PC2414 was shown to have low acute toxicity by the oral route i.e. LD50 greater than 2000 mg/kg bw. Based on this result, TS-ED 532 is not hazardous and is not classified according to GHS and DSD-DPD.