(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol

Particle size distribution (Granulometry)

Administrative data

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

October 10, 2011

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: The test is not performed according to the GLP but performed by ISO 17025 Certified Laboratory

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2011

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: ISO 13320-1

Deviations:

no

GLP compliance:

no

Type of distribution:

volumetric distribution

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

413-110-2

EC Name:

-

Cas Number:

135861-56-2

Molecular formula:

C24H30O6

IUPAC Name:

(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol

Details on test material:

powder

Results and discussion

Particle size

Particle size 1

Percentile:

D50

Mean:

37.71 µm

Remarks on result:

other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.

Particle size 2

Percentile:

D10

Mean:

2.9 µm

St. dev.:

0.16

Particle size 3

Percentile:

D50

Mean:

26.01 µm

St. dev.:

1.35

Particle size 4

Percentile:

D90

Mean:

88.97 µm

St. dev.:

8.1

Applicant's summary and conclusion

Executive summary:

Particle size (µm)

	D10	D50	D90	average particle size
Run1	2.79	25.05	83.24	36.01
Run2	3.01	26.96	94.70	39.40
Average	2.90	26.01	88.97	37.71
Standard Dev.	0.16	1.35	8.10	2.40