Registration Dossier
Registration Dossier
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EC number: 700-790-3 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The 72-hour EC50s for the constituents of GLS-Silane range are >100 mg/L. NOECs ranged from <6.3 mg/L to >118 mg/L.
Key value for chemical safety assessment
Additional information
There are no data for toxicity to aquatic algae and cyanobacteria for GLS-Silane. Data are available for the constituents of GLS-Silane, their hydrolysis products or structurally similar analogues.The hydrolysis half-life of chlorosilanes indicate that, under conditions relevant to the algal toxicity test, hydrolysis to a silanediol and hydrogen chloride will occur. The properties of hydrogen chloride are well characterised. Its effects on aquatic organisms are limited to those that result from changes to pH in unbuffered media.
Silanes comprise 74 -97% w/w of GLS-Silane. The remaining constiuents are hydrocarbons. Three of the hydrocarbons are liqufied gases present at <1%. The other hydrocarbon, 2 -methyl butane is present at >3 -<10% w/w. Therefore, toxicity of GLS-Silane is determined based on the toxicity of its silane constituents or their read-across compounds. EC50 values for the silanes and/or silanols are all > 100 mg/L.
No data for toxicity to aquatic algae and cyanobacteria are available for dichloro(methyl)silane. However a study of toxicity to aquatic algae is available for the related substance dimethylsilanediol. Dimethylsilanediol, 1066-42-8, is a close structural analogue of Methylsilanediol, which is the hydrolysis product of Dichloro(methyl)silane, 75-54-7. The 72-hr EC50 for dimethylsilanediol was >118 mg/L. The NOEC was also >118 mg/L.
Trimethoxysilane was used as a structural analogue for triclorosilane. Both materials break down to silanol. The Algal Growth Inhibition 72-hr EC50 with Pseudokirchnerella subcapitata for trimethoxysilane was >100 mg/L. The NOEC was <6.3 mg/L.
Trimethylsilanediol was used as a structural analogue for chloro(dimethyl)silane. The Algal Growth inhibition 72-hr EC50 with Pseudokirchnerella subcapitata for trimethylsilanediol was >1053 mg/L. The NOEC was 70 mg/L.
An algal growth inhibition study was conducted on Tetramethylsilane with a reported EC50 and NOEC of > 0.0079 mg/L. However, this was the highest concentration tested and no effects were observed at this concentration. This study was not considered in the range of algal toxicity studies for GLS-Silane because of its low value relative to all other test endpoints and the lack of effect at this, the highest concentration tested.
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