Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no hazard identified

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no or insufficient data available at present

Additional information

There are no experimental and/or literature data specific on L-CARNITINEAMIDE D-CAMPHORATED.

The analysis was carried out by calculation tools, but results were not exhaustive, since it is a salt, public programs are outside the application field and can not be used. Therefore it has been evaluated the comparison with the base (Camphor; CAS: 76 -22 -2; EC: 200 -945 -0) and counter-ion (Levocarnitine; CAS: 541 -15 -1; EC: 208 -768 -0) of the substance properties.

Information about environmental fate and pathways are not many and sufficient to trace a complete profile of the substance; nevertheless note that release in eviron of L-Carnitineamide D-Camphorated is not expected.

Data estimated/comparison with base and counter-ion

Data available refrer to Camphor.

Fathead minnow (Pimephales promelas), static bioassays results [*-18]:

LC50: 145 mg/L/1 hr

LC50: 112 mg/L/24 hr

LC50: 111 mg/L/48 hr

LC50: 110 mg/L/72 hr

LC50: 110 mg/L/96 hr

Zebrafish (Brachydanio rerio) LC50: 35-50 mg/L/48-96 hr[*-18].

Conclusion

L-Carnitineamide D-Camphorated is not expected to represent a danger for environmental: it is not resulted toxic to fish, moreover calculation tools estimated that L-Carnitineamide D-Camphorated have a fast half lives metabolism, meaning that is not expected to be bioaccumulable. Furthermore it is also to be considered that Camphor is readly biodegradable.

Any details about data available are reported in the report attached at the point 13: Assessment Report.

Reference

[*] Hazardous Substances Data Bank – HSDB - U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894, National Institutes of Health, Department of Health & Human Services

[18]: Verschueren, K. Handbook of Environmental Data on Organic Chemicals. Volumes 1-2. 4th ed. John Wiley & Sons. New York, NY. 2001, p. 421

Conclusion on classification

L-Carnitineamide D-Camphorated is not expected to represent a danger for environmental.

According to the Regulation EC 1272/2008 (CLP) L-Carnitineamide D-Camphorated is classified as nor danger, nor harmful for aquatic organisms.