Registration Dossier

Diss Factsheets

Classification & Labelling & PBT assessment

GHS

General Information

Name:
Benzalkonium chloride - on-site isolated intermediate
Implementation:
EU
Remarks:
This on-site isolated intermediate is manufactured primarily from C12-C14 alkyldimethylamines in IMS and reacted with benzyl chloride. The substance formed has been shown to be consistent with benzalkonium chloride (BAC) CAS# 68424-85-1, and whilst the analysis of the individual end points has not been carried out on this intermediate it is justified that the classification assigned will be similar to the agreed classification for BAC as detailed in the BPD dossier, Directive 98/8/EC concerning the placing of biocidal products on the market, submitted June 2010.
BAC which is not used for biocides is being REACH registered by the end of May 2013. The classification as published to members of the SIEF has been assessed from the phys-chem, toxicology and eco-toxicology data available in the consortium and has been communicated for use in classifying this substance. However, in addition to the hazards associated with BAC, this classification has also taken into account the contribution of the Industrial Methylated Spirits solvent component and also the fact that there may still be some benzyl chloride impurity present to a max of 0.25%. These two components add the flammability and posiible carcinogenic activity not normally associated with BAC classification.

Related composition

Related composition:
Benzalkonium Chloride On-Site Isolated Intermediate

Classificationopen allclose all

Explosives
Reason for no classification:
data lacking
Flammable gases and chemically unstable gases
Reason for no classification:
data conclusive but not sufficient for classification
Aerosols
Reason for no classification:
data conclusive but not sufficient for classification
Reason for no classification:
hazard class not assessed
Oxidising gases
Reason for no classification:
data conclusive but not sufficient for classification
Gases under pressure
Reason for no classification:
data conclusive but not sufficient for classification
Flammable liquids
Hazard category:
Flam. Liquid 3
Hazard statement:
H226: Flammable liquid and vapour.
Flammable solids
Reason for no classification:
data conclusive but not sufficient for classification
Self-reactive substances and mixtures
Reason for no classification:
data lacking
Pyrophoric liquids
Reason for no classification:
data conclusive but not sufficient for classification
Pyrophoric solids
Reason for no classification:
data conclusive but not sufficient for classification
Self-heating substances and mixtures
Reason for no classification:
data lacking
Substances and mixtures which in contact with water emit flammable gases
Reason for no classification:
data conclusive but not sufficient for classification
Oxidising liquids
Reason for no classification:
data lacking
Oxidising solids
Reason for no classification:
data conclusive but not sufficient for classification
Organic peroxides
Reason for no classification:
data conclusive but not sufficient for classification
Corrosive to metals
Reason for no classification:
data lacking
Desensitized explosives
Reason for no classification:
data lacking
Acute toxicity - oral
Hazard category:
Acute Tox. 4
Hazard statement:
H302: Harmful if swallowed.
Acute toxicity - dermal
Reason for no classification:
data lacking
Acute toxicity - inhalation
Reason for no classification:
data lacking
Skin corrosion / irritation
Hazard category:
Skin Corr. 1B
Hazard statement:
H314: Causes severe skin burns and eye damage.
Serious eye damage / eye irritation
Hazard category:
Eye Damage 1
Hazard statement:
H318: Causes serious eye damage.
Respiratory sensitisation
Reason for no classification:
data lacking
Skin sensitisation
Reason for no classification:
data lacking
Aspiration hazard
Reason for no classification:
data lacking
Reproductive toxicity
Reason for no classification:
data lacking
Effects on or via lactation
Reason for no classification:
data lacking
Germ cell mutagenicity
Reason for no classification:
data lacking
Carcinogenicity
Hazard category:
Carc. 1B
Hazard statement:
H350: May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
Route of exposure:
inhalation
1. Specific target organ toxicity - single (STOT-SE)
Reason for no classification:
data lacking
1. Specific target organ toxicity - repeated (STOT-RE)
Reason for no classification:
data lacking
Hazardous to the aquatic environment (acute / short-term)
Hazard category:
Aquatic Acute 1
Hazard statement:
H400: Very toxic to aquatic life.
Hazardous to the aquatic environment (long-term)
Hazard category:
Aquatic Chronic 1
Hazard statement:
H410: Very toxic to aquatic life with long lasting effects.
Hazardous to the ozone layer
Reason for no classification:
data lacking

Labelling

Signal word:
Danger

Hazard pictogram

GHS02: flame
GHS05: corrosion
GHS08: health hazard
GHS09: environment

Hazard statements

H226: Flammable liquid and vapour.
H302: Harmful if swallowed.
H314: Causes severe skin burns and eye damage.
H350: May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
inhalation
H410: Very toxic to aquatic life with long lasting effects.

Precautionary statements

P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P243: Take actions to pevent static discharges.
P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P280: Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P285: In case of inadequate ventilation wear respiratory protection.
P273: Avoid release to the environment.
P264: Wash ... thoroughly after handling.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P303+P361+P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P301+P330+P331: IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician.
P363: Wash contaminated clothing before reuse.
P501: Dispose of contents/container to ...
authorised waste company in accordance with local/regional/national/international regulations.

Notes