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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Study period:
31st August 1995
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Comparable to guideline study with acceptable restrictions. This study was performed in compliance with the GLP regulations. Only memorandum available; no full study report.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1995
Report date:
1995

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
Deviations:
not specified
Principles of method if other than guideline:
No further details were provided.
GLP compliance:
yes

Test material

Constituent 1
Reference substance name:
PTH-decahydroamide
IUPAC Name:
PTH-decahydroamide
Constituent 2
Reference substance name:
Ro 31-9373/000
IUPAC Name:
Ro 31-9373/000
Details on test material:
No further details were provided.
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
No further details were provided.

Sampling and analysis

Analytical monitoring:
not specified
Details on sampling:
No further details were provided.

Test solutions

Vehicle:
not specified
Details on test solutions:
No further details were provided.

Test organisms

Test organisms (species):
activated sludge
Details on inoculum:
No further details were provided.

Study design

Test type:
not specified
Water media type:
not specified
Remarks on exposure duration:
No further details were provided.
Post exposure observation period:
No further details were provided.

Test conditions

Hardness:
No further details were provided.
Test temperature:
No further details were provided.
pH:
No further details were provided.
Dissolved oxygen:
No further details were provided.
Salinity:
No further details were provided.
Nominal and measured concentrations:
No further details were provided.
Details on test conditions:
No further details were provided.
Reference substance (positive control):
not specified

Results and discussion

Details on results:
No significant inhibition in respiration rate of the sludge (> 10 %) was recorded at 100 mg PTH-decahydroamide (Ro 31-9373/000) per litre.
Results with reference substance (positive control):
No further details were provided.
Reported statistics and error estimates:
No further details were provided.

Any other information on results incl. tables

No further details were provided.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
No significant inhibition in respiration rate of the sludge (> 10 %) was recorded at 100 mg PTH-decahydroamide (Ro 31-9373/000) per litre. Thus under the conditions of the test PTH-decahydroamide (Ro 31-9373/ 000) was not toxic to waste water bacteria.
Executive summary:

The study procedure described was performed on the basis of EC directive 87/302/EEC, Part C (adopted 1988) and OECD guideline No. 209 (1984). No significant inhibition in respiration rate of the sludge (> 10 %) was recorded at 100 mg PTH-decahydroamide (Ro 31-9373/000) per litre. Thus under the conditions of the test PTH-decahydroamide (Ro 31-9373/ 000) was not toxic to waste water bacteria.