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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

EC50 for freshwater algae:
35 mg/L
EC10 or NOEC for freshwater algae:
10 mg/L

Additional information

Based on Read-Across with 2,2-Bis(chloromethyl)trimethylene bis[bis(2-chloroethyl)phophate

Test data

Growth inhibition tests have been carried out with two species of unicellular freshwater algae, Scenedesmus subspicatus and Pseudokirchnierella subcapitata. The test with P. subcapitata (L'Haridon 2002) was conducted over a range of test concentrations, was supported by analysis of exposure concentrations and was subject to GLP. The test gave a 72-hour ErC50value of 35 mg/l and a 72-hour NOEC of 10 mg/l. These results provide a suitable basis for deriving a PNECwater.


QSAR estimated toxicity

Estimated 96-hour EC50and NOEC values of 2.6 and 2.1 mg/l have been derived for algae using an ECOSAR QSAR applicable to esters. The estimated values are lower than those obtained in the reported studies.



European Union Risk Assessment Report "2,2-Bis(chloromethyl)trimethylene bis[bis(2-chloroethyl)phophate]" (V6), CAS 38051-10-4, May 2008