Registration Dossier
Registration Dossier
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EC number: 809-920-4 | CAS number: 1047637-37-5
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
23-day NOEC for reproduction of >=3.68 mg/l
Key value for chemical safety assessment
Additional information
Based on Read-Across with 2,2-Bis(chloromethyl)trimethylene bis[bis(2-chloroethyl)phophate
Test data
One chronic invertebrate test with Daphnia magna (L’Haridon, 2003) has been performed. The test fulfilled all the acceptability criteria for determining a PNEC. There were no significant effects on reproduction at a concentration that was lower than that that significantly affected adult mortality. A 23-day NOEC for reproduction of >=3.68 mg/l was therefore determined.
QSAR estimated chronic toxicity
An estimated value of 6.0 mg/l has been derived for long term reproductive effects in invertebrates using an ECOSAR QSAR applicable to neutral organics. This value may not be of high reliability because the QSAR is not recommended by ECOSAR for this type of compound, and it has not been well validated.
Reference:
European Union Risk Assessment Report "2,2-Bis(chloromethyl)trimethylene bis[bis(2-chloroethyl)phophate]" (V6), CAS 38051-10-4, May 2008
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