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Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
52 mg/L

Additional information

Based on Read-Across with 2,2-Bis(chloromethyl)trimethylene bis[bis(2-chloroethyl)phophate

Test data

Two acute toxicity tests have been carried out with the fish species Oncorhynchus mykiss (Rainbow trout).

One of the tests (L'Haridon, 2002) was conducted over a range of test concentrations, was supported by analysis of exposure concentrations and was subject to GLP. The test gave a 96-hour LC50value of 52 mg/l. This result provides a suitable basis for deriving a PNECwater.



Estimated values of 32 and 17 mg/l have been derived for acute (96-hour LC50) fish toxicity using ECOSAR QSARs applicable to esters and phosphate esters respectively. The values are consistent with those obtained in the reported studies.



European Union Risk Assessment Report "2,2-Bis(chloromethyl)trimethylene bis[bis(2-chloroethyl)phophate]" (V6), CAS 38051-10-4, May 2008