Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records
Reference
Endpoint:
acute toxicity: oral
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Qualifier:
no guideline followed
Guideline:
other: no data
Deviations:
not specified
GLP compliance:
not specified
Species:
rat
Strain:
not specified
Sex:
not specified
Route of administration:
other: no data
Vehicle:
not specified
Sex:
not specified
Dose descriptor:
LD50
Effect level:
14.6 mg/kg bw
Based on:
not specified
Remarks on result:
other: no data
Endpoint conclusion
Dose descriptor:
LD50
Value:
14.6 mg/kg bw

Acute toxicity: via inhalation route

Link to relevant study records
Reference
Endpoint:
acute toxicity: inhalation
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Qualifier:
no guideline followed
Guideline:
other: no data
Deviations:
not specified
GLP compliance:
no
Test type:
fixed concentration procedure
Species:
rat
Strain:
not specified
Sex:
not specified
Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
air
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
ca. 1 h
Sex:
not specified
Dose descriptor:
LC50
Effect level:
> 2.2 mg/L air
Based on:
not specified
Exp. duration:
1 h
Remarks on result:
other: no data
Endpoint conclusion
Dose descriptor:
LC50
Value:
2.2 mg/m³

Acute toxicity: via dermal route

Link to relevant study records
Reference
Endpoint:
acute toxicity: dermal
Data waiving:
other justification
Justification for data waiving:
other:
Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: OECD GHS
Endpoint conclusion

Additional information

Evaluating acute toxicity of pyrite cinder is possible classify this substance as highly dangerous for oral and inhalation exposure.

Justification for classification or non-classification