Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vitro / ex vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Safety data sheet of the supplier
Title:
Safety data sheet of the ketoamide
Author:
Merck
Year:
2009
Bibliographic source:
Safety data sheet of the supplier
Report date:
2009

Materials and methods

Principles of method if other than guideline:
No data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione
Cas Number:
764667-65-4
Molecular formula:
C16H12F6N4O2
IUPAC Name:
1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione

Test animals / tissue source

Species:
other: bovine
Strain:
not specified

Test system

Vehicle:
not specified

Results and discussion

In vivo

Results
Remarks on result:
other: not irritating

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
not irritating