Registration Dossier

Administrative data

Description of key information

Oral (Rat, GLP, OECD TG 423): LD50 > 2000 mg/kg
[Schering AG, Report No. X174 -draft-, 1996-10-21]

Key value for chemical safety assessment

Additional information

The single oral administration of the test substance (ZK 5668) to male and female rats at a dose of 2000 mg/kg was tolerated without any mortality.

No compound-related clinical signs and effects on body weight were observed and there were no macroscopic pathological signs.

The acute oral toxicity of 1,4,6 -Trienol in rats is therefore above 2000 mg/kg body weight.

Justification for classification or non-classification

Based on the study results a classification according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (CLP) is not required.