Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 696-577-7 | CAS number: 34335-10-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 02 November 2007 to 30 November 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study undertaken at GLP accredited laboratory to internationally recognised guidelines.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 305 (Bioconcentration: Flow-through Fish Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Phenylphosphonic acid, zinc salt
- IUPAC Name:
- Phenylphosphonic acid, zinc salt
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): Phenylphosphonic acid zinc salt
- Substance type: Inorganic
- Physical state: Powder
- Analytical purity: > 98%
- Purity test date: No data
- Lot/batch No.: 0Q2YD
- Expiration date of the lot/batch:
- Stability under test conditions: Stable
- Storage condition of test material: Room temperature.
Constituent 1
- Radiolabelling:
- no
Sampling and analysis
- Details on sampling:
- - Sampling intervals/frequency for test organisms: 4 and 3 days alternately.
- Sampling intervals/frequency for test medium samples: 4 and 3 days alternately.
- Sample storage conditions before analysis:
- Details on sampling and analysis of test organisms and test media samples (e.g. sample preparation, analytical methods):
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Cyprinus carpio
- Details on test organisms:
- TEST ORGANISM
- Common name: Carp
- Source: Commercial fish farm
- Age at study initiation (mean and range, SD): < 1 year
- Length at study initiation (lenght definition, mean, range and SD): average 7.5 cm
- Weight at study initiation (mean and range, SD): average 5.4 g
- Weight at termination (mean and range, SD):
- Method of breeding:
- Health status: good
- Description of housing/holding area: The fish were reared for 32 days in a static water chamber. (with circulating water cleaning filtering system)
- Feeding during test
- Food type: The formula feed for carp [manufactured by Nosan Corporation: crude protein of above 39.0%, crude fat of above 3.0%] added with animal fat and oil for cultivated aquatic animals [Riken Feed Oil Q: manufactured by Riken Vitamin Co., Ltd.]
- Amount: 5% w/w
- Frequency: 5% (w/w) was fed daily at the amount corresponding to about 1 - 2% of the body weight of the test fish. The amount was divided into halves, and feeding was twice in a day.
ACCLIMATION
- Acclimation period: 32 days
- Acclimation conditions (same as test or not): After rearing, the fish demonstrating any abnormalities were removed and fish to be assigned to the study groups were transferred in acclimatization chamber. An external disinfection was carried out for four days(October 12, 2007~ October 16,2007)before start to acclimatization. (Name of disinfectant: Sodium chloride, Concentration: 5.0glL, Temperature: 25'C)] Subsequently,
they were reared for 17 days in a flow through system.
- Type and amount of food: as above
- Feeding frequency: as above
- Health during acclimation (any mortality observed): no data
Study design
- Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 28 d
Test conditions
- Hardness:
- 72 mg/l
- Test temperature:
- ~ 25 °C
- pH:
- 7.49
- Dissolved oxygen:
- 8.1 mg/l
- TOC:
- < 0.3 mg/l
- Salinity:
- < 0.01 mg/l
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 100 litre tank
- Material, size, headspace, fill volume: glass
- Aeration: no
- Type of flow-through (e.g. peristaltic or proportional diluter): 600 ml / min
- Renewal rate of test solution (frequency/flow rate): 72 ml / h
- No. of organisms per vessel: 45
- No. of vessels per concentration (replicates): 1
- No. of vessels per control / vehicle control (replicates): 1
- Biomass loading rate:
TEST MEDIUM / WATER PARAMETERS
- Particulate matter: < 1.0mg/l
- Metals:
- Pesticides:
- Chlorine: < 0.01 mg/l
- Alkalinity: 7.49
- Ca/mg ratio:
- Conductance:
- Holding medium different from test medium: yes
- Intervals of water quality measurement: 3/4 days
- Intervals of test medium replacement: flow-through
OTHER TEST CONDITIONS
- Adjustment of pH:
- Photoperiod: 16 h/day
- Light intensity: no data
RANGE-FINDING / PRELIMINARY STUDY
- Test concentrations:
- Results used to determine the conditions for the definitive study: - Nominal and measured concentrations:
- No data
- Reference substance (positive control):
- no
- Details on estimation of bioconcentration:
- BASIS FOR CALCULATION OF BCF
Bioconcentration factors (BCF) of test substance in test fish were calculated using equations. Results were rounded off to 2 digits. From the detection limit concentration of test substance in fish body, if exceeded following magnifications, BCF could be calculated. (In case that the fish weight is 20.0 g).
Level 1 concentration: 3.1 fold
Level 2 concentration: 31 fold
Results and discussion
Lipid contentopen allclose all
- Lipid content:
- 3.4 %
- Time point:
- start of exposure
- Lipid content:
- 3.1
- Time point:
- end of exposure
Bioaccumulation factoropen allclose all
- Type:
- BCF
- Value:
- 5 dimensionless
- Basis:
- whole body w.w.
- Calculation basis:
- steady state
- Remarks on result:
- other: Conc.in environment / dose:0.030 mg/l
- Type:
- BCF
- Value:
- < 48 dimensionless
- Basis:
- whole body w.w.
- Calculation basis:
- steady state
- Remarks on result:
- other: Conc.in environment / dose:0.0030 mg/l
- Details on kinetic parameters:
- No data
- Metabolites:
- No data
- Results with reference substance (positive control):
- No positive control
- Details on results:
- - Mortality of test organisms: none
- Behavioural abnormalities: none
- Observations on body length and weight:
- Other biological observations:
- Organ specific bioaccumulation:
- Bound residues forming a plateau:
- Mortality and/or behavioural abnormalities of control:
- Loss of test substance during test period:
- Results with vehicle control:
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Bioconcentration factors in a steady state were;
Level 1 concentration (0.030 mg/l) 5.0 fold;
Level 2 concentration (0.0030 mg/l): Less than 48 fold
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
