Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

A guinea pig maximization study was conducted using current OECD 406 guidelines to examine the potential of KGA to cause sensitization to skin. A group of 20 female guinea pigs were exposed to a concentration of 50% of test substance. The induction phase consisted of two intradermal injections followed by dermal application. Seven days later, the animals were challenged by dermal application. No signs of irritation were seen in any animals during the challenge phase. The test substance is not sensitising to skin according to current guidelines.


Migrated from Short description of key information:
A skin sensitization study in guinea pigs is available for KGA. No signs of irritation were seen in any animals during the challenge phase. The test substance is not sensitising to skin under current guidelines.

Justification for classification or non-classification

KGA and KGA Greens is not classified as a skin sensitizer due to the lack of significant effects during a guinea pig maximization study.