Registration Dossier

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
key study
Study period:
May 1997 to June 1997
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study at company laboratory

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1997

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: DIN EN ISO 10712 (February 1996)
Deviations:
yes
Remarks:
The pH of the nominal 313 ug/l sample was less than 4 at the start of test
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
The study was conducted on KGA, which is the major constituent of KGA Greens.

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Pseudomonas putida

Study design

Test type:
static
Water media type:
not specified
Limit test:
yes
Total exposure duration:
16 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
16 h
Dose descriptor:
EC10
Effect conc.:
ca. 166 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: Inhabition of cell proliferation
Duration:
16 h
Dose descriptor:
EC50
Effect conc.:
ca. 220 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: Inhabition of cell proliferation
Duration:
16 h
Dose descriptor:
other: EC90
Effect conc.:
ca. 293 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: Inhabition of cell proliferation

Applicant's summary and conclusion

Validity criteria fulfilled:
yes