Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 425-380-9 | CAS number: 7397-46-8
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Remarks:
- other: ex-vivo
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Information from migrated NONS file.
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
- Principles of method if other than guideline:
- Due to the pyrophoric nature of the test substance (instable in air) an 'ex-vivo' study using non-living animals and
non-living animal skin was performed.
Test material
- Reference substance name:
- -
- EC Number:
- 425-380-9
- EC Name:
- -
- Cas Number:
- 7397-46-8
- Molecular formula:
- C5H13BO
- IUPAC Name:
- methyl diethylborinate
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information
- Conclusions:
- Due to the pyrophoric nature of the test substance (instable in air) an 'ex-vivo' study using non-living animals and non-living animal skin was performed. The notified substance was found to be corrosive to skin and for humane reasons a study was not performed. The LD50 is expected to lie between 200 and 2000 mg/kg and the susbtance is classied as harmful.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
