Registration Dossier
Registration Dossier
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EC number: 700-603-5 | CAS number: 908145-87-9
Endpoint summary
Administrative data
Description of key information
Based on test data from Acute Toxic Class Determination Study, Intermediate is not classified as acutely toxic under EU CLP Regulations
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Additional information
An Acute Toxic Class Determination Study was conducted as per OECD Guideline 423.
Results Summary:
300 mg/kg: All six animals survived the single 300 mg/kg oral dose. No physical signs were observed. Body weight changes were normal in 5/6 animals. One animal lost weight. Necropsy results were normal in 5/6 animals. One animal was noted with a larger than normal thymus.
2000 mg/kg: All six animals survived the single 2000 mg/kg oral dose. No physical signs were observed. Body weight changes were normal for both sexes. Necropsy results were normal.
Conclusion:
The LD50 is greater than 2000 mg/kg. Compound 2945989, Lot# Z84-H70580-095 is considered to be in Acute Toxic Category 5 or unclassified under EU CLP Regulations.
Justification for classification or non-classification
The LD50 is greater than 2000 mg/kg. Intermediate 2945989, is considered to be in GHS Acute Toxic Category 5 or unclassified under EU CLP Regulations.
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