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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Qualifier:
according to
Guideline:
other: CIPAC MT 187
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of particle tested:
agglomerate
Mass median aerodynamic diameter:
9.089 µm
Geometric standard deviation:
0.01
Key result
Percentile:
D10
Mean:
< 2.723 µm
St. dev.:
0.045
Key result
Percentile:
D50
Mean:
< 8.163 µm
St. dev.:
0.082
Key result
Percentile:
D90
Mean:
< 21.607 µm
St. dev.:
0.466
Executive summary:

 Particle Size Analysis using dry powder module

(DPM)

 Average (μm)
 Volume weighted mean  12.156
 Median (d.50)  8.163
 Mode  8.283
 MMAD (Mass Median Aerodynamic Diameter)  9.089
 10 % of material is <  2.723
 50 % of material is <  8.163
 90 % of material is <  21.607
 volume of sample < 10.00 μm  60.49 %

Description of key information

 Particle Size Analysis using dry powder module

(DPM)

 Average (μm)
 Volume weighted mean  12.156
 Median (d.50)  8.163
 Mode  8.283
 MMAD (Mass Median Aerodynamic Diameter)  9.089
 10 % of material is <  2.723
 50 % of material is <  8.163
 90 % of material is <  21.607
 volume of sample < 10.00 μm  60.49 %

Additional information