Registration Dossier
Registration Dossier
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EC number: 411-410-8 | CAS number: 118562-73-5
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96 h LC50 value was determined at a nominal concentration of 0.33 mg/l. This corresponds to an actual concentration of 0.21 mg/l.
The corrected actual NOEC is calculated at 0.065 mg/l.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.21 mg/L
Additional information
The acute fish toxicity of Hydroxyambran was determined according to the OECD Test Guideline 203 using Rainbow trout (Oncorhynchus mykiss) as test fish.
During the preliminary test, a mortality of 100 % was observed at the highest concentration level (saturated solution, approxm. nominal 1 g/l), whereas a mortality of 20 % was observed at a dilution of 1:10, within 96 h.
The main test was performed under semi-static conditions (daily renewal of the test solutions) with 6 concentration levels of the test article based on nominal values between 1.030 mg/l and 0.058 mg/l. The serial dilution factor was 1.78.
The LC50 values were calculated as geometric mean from the LC0 and LC100. The 96 h LC50 value was determined at a nominal concentration of 0.33 mg/l. This corresponds to an actual concentration of 0.21 mg/l.
On the basis of the observations performed during the main test, the NOEC was determined at a nominal concentration of 0.103 mg/l. The corrected actual NOEC is calculated at 0.065 mg/l.
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