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EC number: 940-733-1
CAS number: -
A Magnusson and Kligman Guinea-Pig Maximization test was conducted on 20
guinea pigs with Shellsol TD. Twenty guinea pigs were treated by
intradermal injection (1.0% (w/v) Shellsol TD in vehicle) to induce
sensitization and then further sensitized by dermal application of 50.0%
(w/v) Shellsol TD. Guinea Pigs were challenged by topical application
(25.0% (w/v) Shellsol TD in corn oil). All animals survived to
termination of study. There was a very low incidence of clinical
in-life observations noted throughout the test period. Following
topical challenge with 25.0% (w/v) Shellsol TD, all animals were free of
dermal irritation. Classification as a skin sensitizer is not warranted
under the new Regulation (EC) 1272/2008 on classification, labeling and
packaging of substances and mixtures (CLP) or under Directive 67/548/EEC
for dangerous substances and Directive 1999/45/EC for preparations.
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