Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.26
Temp.:
35 °C
pH:
2.5

Applicant's summary and conclusion

Conclusions:
The Logarithm of the Octanol Water partition coefficient of the organic part of PACTT, 2 Na has been determined on the acid, non salified form of this organic part at pH 2.5 to be in the worst case, as recommended in the guidelines. It has been found to be 2.26 with the OECD 117 HPLC method. The inorganic part of PACTT, 2 Na being very soluble in water and insoluble in Octanol, 2.26 can be taken as an overall worst case value for the multi-constituents substance.

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