Registration Dossier
Registration Dossier
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EC number: 940-217-6 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Under the conditions of this study, the 96 hour LL50 was determined to be 2.0 mg/L loading rate WAF with 95 % confidence limits of 1.7 to 2.5 mg/L loading rate WAF. The Lowest Observed Effect Loading rate was 1.8 mg/L loading rate WAF and the No Observed Effect Loading rate was 1.0 mg/L loading rate WAF.
As a result of the LL50 value, in conjunction with the substance's physico-chemical properties, the test material requires classification for being hazardous to the aqueous environment and as such is categorised as Chronic Category 2 in accordance with EU criteria.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2 mg/L
Additional information
The acute toxicity potential of the test material to Oncorhynchus mykiss was investigated in accordance with the standardised guidelines OECD 203 and EU Method C.1 under GLP conditions. It was assigned a reliability score of 1 in accordance with the criteria set forth in Klimisch (1997).
Fish were exposed in groups of seven to Water Accommodated Fractions (WAFs) of the test material over a range of nominal loading rates of 0.56, 1.0, 1.8, 3.2 and 5.6 mg/L for a period of 96 hours at 14 to 15 °C under semi-static test conditions. The number of mortalities and any sub-lethal effects of exposure in each test and control vessel were determined 3 and 6 hours after the start of exposure and then daily throughout the test until termination after 96 hours.
Given that toxicity cannot be attributed to a single component or a mixture of components but to the test material as a whole, and the dissolved test material was around the quantifiable limit of the analytical method, the results were based on nominal loading rates only.
Under the conditions of this study, the 96 hour LL50 was determined to be 2.0 mg/L loading rate WAF with 95 % confidence limits of 1.7 to 2.5 mg/L loading rate WAF. The Lowest Observed Effect Loading rate was 1.8 mg/L loading rate WAF and the No Observed Effect Loading rate was 1.0 mg/L loading rate WAF.
As a result of the LL50 value, in conjunction with the substance's physico-chemical properties, the test material requires classification for being hazardous to the aqueous environment and as such is categorised as Chronic Category 2 in accordance with EU criteria.
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