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Environmental fate & pathways

Monitoring data

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Administrative data

Endpoint:
monitoring data
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The study and data are well documented and scientifically acceptable.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD306 (A degradation test in sea water)
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Applicant's summary and conclusion

Executive summary:

Wastewater from production of x-ray contrast agents have been found to have an inhibiting effect on the reproduction of marine copepods. The present investigation was performed to examine if biological degradation will reduce the concentration of contrast agents and the reproduction inhibiting effect of the wastewater. A degradation test in seawater (OECD Guideline 306), showed 84% reduction in the concentrations of contrast agents over 59 days at 20C. The inhibition of reproduction of the copepod Nitocra spinipes was not significantly affected by 28days biological degradation of the wastewater. It was concluded that the effects on the reproduction propably is caused by the residual contrast agents in the wastewater.

A thin-layer chromatography assay showed low concentrations of potentially bioaccumulative substances in the wastewater.