Registration Dossier
Registration Dossier
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EC number: 700-347-4 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The test substance was found to be non-mutagenic and non-clastogenic.
In the Ames test, the test substance was not considered to be mutagenic to bacteria under the conditions of the test. The test substance was not found to be clastogenic in an in vitro mammalian chromosome aberration test in human peripheral lymphocytes. The test substance was found not to be mutagenic in an in vitro cell gene mutation test performed using mouse lymphoma cells.
Overall, the test substance is considered non-mutagenic and non-clastogenic.
Justification for selection of genetic toxicity endpoint
No study was selected, since all three in vitro studies were negative
Short description of key information:
Clearly negative in the in vitro studies - both with and without metabolic activation
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
The test data does not support classification of the registered substance as mutagenic according to the criteria laid down in Regulation (EC) No 1272/2008 (i.e. CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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