Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 216-316-9 | CAS number: 1558-25-4
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
3-hr EC50 of > 1000 mg/l and a NOEC of ≥ 1000 mg/l (OECD 209), RL1
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
No data is available for trichloro(chloromethyl)silane (CAS No. 1558 -25). However, due to fast hydrolysis read across to the hydrolysis product (chloromethyl)trisilanol is warranted accoring to ECHA guidance that states that “for substances where hydrolytic DT50is less than 12 hours, environmental effects are likely to be attributed to the hydrolysis product rather than to the parent itself." Hydrochloric acid is not classified for environmental hazards. Data relevant for the assessment of the other hydrolysis product (chloromethyl)trisilanol can be taken from a tests with (chloromethyl)triethoxysilane (CAS No. 15267-95-5) which has a hydrolysis half-life of approximately 2.5 h at 20-25°C and pH 7 and thus predominatly gives information on the same silanol hydrolysis product. The other hydrolysis product is not classified for environmental hazards and thus not relevant for the assessment.
´ The study was conducted to standard guideline (OECD 209), GLP and fulfilled the validity criteria (NOTOX, 2011). There was no observed effect of respiration rate of tested microorganisms at the test concentration after 3 hours, and so the EC50and NOEC values were assessed to be >1000 mg/l and ≥1000 mg/l.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
