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Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

The Buehler test is a non-adjuvant method involving the induction phase topical application only. It gives qualitative assessment of skin sensitization after induction - rest - revelation phases. The test was performed using olive oil as vehicule.

The LLNA is a method involving the lymphocyte proliferative responses indused in regional lymph nodes. It gives a quantitative assessment of skin sensitization after an induction phase. The test was performed using dimethylformamide (DMF) as vehicule.


Migrated from Short description of key information:
Sepisol Fast Violet 2B was not found tobe sensitizing with the Buehler test but was considered to be sensitizing with the LLNA test.

Justification for classification or non-classification

The LLNA is the reference test method. Futhermore, there is no hindsight with this organiocopper dye molecules so it was not possible to choose which test fits the best.

As a result the Sepisol Fast Violet 2B is considered to be sensitizing cat. 1A.