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Administrative data

Link to relevant study record(s)

Description of key information

Short description of key information on bioaccumulation potential result: 
In a published study the formation of sulfur containing metabolites in female rabbits and rats was investigated.
Animals received a single dose of 2 mmol (220mg) per kg bw, 24h urine was collected and analysed. More than 80% of the dose was recovered as sulfur containing metabolites of which 2-hydroxy and 3-hydroxy-mercapturic acids were identified.

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential

Additional information

More than 80% of an oral dose of 2 mmol cyclooctene (220mg)/kg bw was excreted within 24h as sulfur containing metabolites indicating extensive absorption and extensive metabolism including hydroxylation as well as rapid excretion.