Registration Dossier

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
It is well established that saturated perfluorocarbons form a class of chemicals with very similar properties.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1989
Report date:
1989

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Docosafluorododecahydrofluorene
EC Number:
405-610-4
EC Name:
Docosafluorododecahydrofluorene
Cas Number:
307-08-4
Molecular formula:
C13F22
IUPAC Name:
1,1,2,2,3,3,4,4,4A,4B,5,5,6,6,7,7,8,8,8A,9,9,9A-Docosafluorododecahydro-1H-fluorene
Test material form:
liquid

Test organisms

Test organisms (species):
activated sludge of a predominantly domestic sewage

Study design

Test type:
static
Water media type:
freshwater
Total exposure duration:
3 h

Test conditions

Hardness:
350 mg/l as CaCO3
pH:
6.0 - 8.5
Reference substance (positive control):
yes
Remarks:
3,5-Dichlorophenol

Results and discussion

Effect concentrations
Key result
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Results with reference substance (positive control):
Reference substance found to have EC(30) of 26 mg/l after 30 minutes, and 15 mg/l after 3 hours.

Applicant's summary and conclusion

Conclusions:
No effect on microorganisms
Executive summary:

No effect on microorganisms