Registration Dossier
Registration Dossier
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EC number: 206-575-6 | CAS number: 355-04-4
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- It is well established that saturated perfluorocarbons form a class of chemicals with very similar properties.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 1989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Docosafluorododecahydrofluorene
- EC Number:
- 405-610-4
- EC Name:
- Docosafluorododecahydrofluorene
- Cas Number:
- 307-08-4
- Molecular formula:
- C13F22
- IUPAC Name:
- 1,1,2,2,3,3,4,4,4A,4B,5,5,6,6,7,7,8,8,8A,9,9,9A-Docosafluorododecahydro-1H-fluorene
- Test material form:
- liquid
Constituent 1
Test organisms
- Test organisms (species):
- activated sludge of a predominantly domestic sewage
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 3 h
Test conditions
- Hardness:
- 350 mg/l as CaCO3
- pH:
- 6.0 - 8.5
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorophenol
Results and discussion
Effect concentrations
- Key result
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Results with reference substance (positive control):
- Reference substance found to have EC(30) of 26 mg/l after 30 minutes, and 15 mg/l after 3 hours.
Applicant's summary and conclusion
- Conclusions:
- No effect on microorganisms
- Executive summary:
No effect on microorganisms
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