Registration Dossier
Registration Dossier
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EC number: 910-404-7 | CAS number: -
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: It is not clear whether sulfide concentrations were measured or not.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Bestimmung der Biologischen Schadwirkung Wassergefährdender Stoffe gegen Protozoen.
- Author:
- Bringmann G
- Year:
- 1 978
- Bibliographic source:
- Zeitschrift für Wasser- und Abwasser-Forschung 11: 210-215
- Reference Type:
- publication
- Title:
- Comparison of the toxicity thresholds of water pollutants to bacteria, algae, and protozoa in the cell multiplication inhibition test.
- Author:
- Bringmann G, Kühn R
- Year:
- 1 980
- Bibliographic source:
- Water Research 14: 231-241
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Cell multiplication inhibition test.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1313-84-4
- Cas Number:
- 1313-84-4
- IUPAC Name:
- 1313-84-4
- Reference substance name:
- sodium sulfide nonahydrate
- IUPAC Name:
- sodium sulfide nonahydrate
- Details on test material:
- - Name of test material (as cited in study report): Na2S.9H2O
Constituent 1
Constituent 2
Test organisms
- Test organisms (species):
- Entosiphon sulcatum
- Details on inoculum:
- holozoic flagellate protozoan feeding on bacteria
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 14 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- other: S2-
- Basis for effect:
- growth inhibition
Applicant's summary and conclusion
- Conclusions:
- This study reports a 72-h EC50 of 14 mg S2-/L based on cell multiplication inhibition data for the flagellate protozoan Entosiphon sulcatum. It is not clear whether sulfide concentrations were measured or not. Moreover only the initial pH was reported. Consequently, the reported EC50 cannot be recalculated to the corresponding H2S concentration in a reliable way.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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