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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Deviations:
not specified
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
N-[2-amino-4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl]-4-methoxybenzamide
EC Number:
616-054-9
Cas Number:
74149-74-9
Molecular formula:
C19 H20 N4 O3
IUPAC Name:
N-[2-amino-4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl]-4-methoxybenzamide
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
brown odorless powder

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
not specified
Water media type:
not specified
Total exposure duration:
48 h

Test conditions

Hardness:
Total hardness from 0.01 to 0.5 °F.
pH:
At the start of the test, pH varied between 7.20 and 7.34; after 48 hours of incubation and exposure to animals, ranged between 7.08 and 7.99.
Dissolved oxygen:
At the start of the test, the dissolved oxygen concentration ranged from 7.6 mg/l and 8.1 mg/l; after 48 hours of incubation and exposure to animals ranged between 6.0 mg/l and 6.3 mg/l.

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
1.058 mg/L
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 100 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The test substance has an EC50 > 100 mg/l at 48 h.
Executive summary:

The test substance Aminopyridazinone has an EC50 > 100 mg/l at 48 hours.

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