Registration Dossier
Registration Dossier
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EC number: 201-178-4 | CAS number: 79-11-8
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary source only
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Chloroacetic acid, CAS No: 79-11-8
- Author:
- OECD SIDS
- Year:
- 1 996
- Bibliographic source:
- http://www.inc hem.org/doc uments/sids/s ids/79118.pdf
- Reference Type:
- publication
- Title:
- Toxicity and pharmacokinetics of monochloracetic acid
- Author:
- Berardi, M. & Snyder, R.
- Year:
- 1 983
- Bibliographic source:
- Pharmacologist, 25, 228
Materials and methods
- Principles of method if other than guideline:
- Rats were exposed to the test substance by the dermal route to evaluate acute dermal toxicity.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Chloroacetic acid
- EC Number:
- 201-178-4
- EC Name:
- Chloroacetic acid
- Cas Number:
- 79-11-8
- Molecular formula:
- C2H3ClO2
- IUPAC Name:
- chloroacetic acid
- Details on test material:
- - Name of test material (as cited in study report): Chloracetic acid
- Analytical purity: no data
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Doses:
- 200 mg/kg bw
Results and discussion
- Mortality:
- Topical application of 200 mg/kg bw caused death (no further information given).
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
