Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 923-201-3 | CAS number: 1192143-92-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Not inherently biodegradable:
16.6% biodegradation in 28 days (OECD 302 C; ThOD NH4)
14.8% biodegradation in 28 days (OECD 302 C; ThOD NO3)
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
No experimental study investigating the ready biodegradability of
UMA 121 is available. However, a study investigating the inherent
biodegradability of UMA 121 is available. This study was carried out
according to OECD Guideline 302C and GLP (Hammesfahr, 2013). Aerobic
activated sludge from a domestic wastewater treatment plant was used as
inoculum. Biodegradation after the 28-day test period was determined to
be 16.6% or in case of nitrification 14.8%. In accordance with ECHA
Guidance R.7b (ECHA, 2016) degradation of < 20% in an inherent
biodegradability test according to OECD 302 would provide sufficient
information to confirm persistence. Thus, additional tests investigating
the ready biodegradability of UMA 121 and/or simulation tests in water,
sediment and soil are not considered to be necessary based on the result
from the inherent biodegradation study. In conclusion, UMA 121 is
considered to be persistent in the environment.
HPMA as a constituent of UMA 121 might be freely available in the
aquatic environment. However, experimental data show that HPMA is
readily biodegradable according to the OECD criteria (Chemicals
Evaluation and Research Institute Japan, 1995 & Rohm, 1994). Thus, it is
expected that the substances is degraded quickly by activated sludge
microorganisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
