Registration Dossier

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Study period:
1996-10-11
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study has been performed in accordance with OECD-Guidline209 without any deviations and under GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996
Report Date:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
Deviations:
no
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Type:
Constituent
Details on test material:
Similar Product based on C13-Alcohol instead of C12-13-Alcohol.

Test organisms

Test organisms (species):
activated sludge of a predominantly domestic sewage

Study design

Test type:
static
Water media type:
brackish water
Total exposure duration:
3 h

Test conditions

Test temperature:
18-22°C
Reference substance (positive control):
yes
Remarks:
Copper(II)sulfate pentahydrate

Results and discussion

Effect concentrations
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
>= 26 - <= 30 mg/L
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate

Applicant's summary and conclusion

Conclusions:
The EC50 of the test substance is 26-30mg/l based on the OECD 209 study.
Executive summary:

The EC50 of the test substance is 26-30mg/l based on the OECD 209 study.