Registration Dossier
Registration Dossier
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EC number: 700-737-4 | CAS number: 1220100-43-5
Endpoint summary
Administrative data
Description of key information
Based upon the combined weight of evidence of the in vitro basal cytotoxicity test using Neutral Red Uptake in Balb/c 3T3 mouse fibroblasts, the substance is considered to have a low order of acute oral toxicity, when it is considered the in vitro study indicates an estimated rodent oral LD50 of 8840 mg/kg and during the 7 day repeated dose study it was found that all animals survived to the 7 day point at the highest dose of 1320 mg/kg/bw.
Key value for chemical safety assessment
Additional information
Based on the available information, the substance is likely to have a low order of acute toxicity. There are no available data on dermal toxicity, but testing appears unwarranted for the current registration under REACH. Inhalation is not a relevant route of exposure.
Justification for classification or non-classification
The substance does not meet classification criteria under EU Directive 67/548/EEC for acute toxicity.
The substance does not meet classification criteria under Regulation (EC) No 1272/2008 for acute toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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